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CHRONIC PAIN: MECHANISMS, IMPACT, AND MANAGEMENT STRATEGIES

Authors

  • Asatullayev Rustamjon Baxtiyarovich

    Trainee assistant at Samarkand State Medical University
    Author
  • Amonova Anisa Azamovna

    Student
    Author

Keywords:

chronic pain, neuropathic pain, treatment, stress, pain psychology, quality of life

Abstract

Chronic pain is a complex, multifactorial condition in which pain persists for more than three months and often becomes an independent disorder rather than a symptom. It exerts a profound impact on an individual’s physical and psychological well-being, reducing quality of life and functional capacity. This paper examines the anatomical and physiological mechanisms of chronic pain, its classification, primary causes, and modern therapeutic approaches. The findings highlight that effective pain control requires a comprehensive strategy combining pharmacological treatment, psychotherapy, physiotherapy, and lifestyle modification.

References

1. World Health Organization (WHO). Chronic Pain: Key Facts. Geneva, 2023.

2. Guyton, A. C., & Hall, J. E. (2020). Textbook of Medical Physiology (14th ed.). Elsevier.

3. Bonica, J. J. (2018). Management of Pain. Lippincott Williams & Wilkins.

4. Treede, R.-D. (2019). Chronic Pain as a Disease. Pain.

5. Mayo Clinic. (2022). Chronic Pain: Causes and Treatment.

6. Woolf, C. J. (2018). Central Sensitization: Implications for the Diagnosis and Treatment of Pain. Pain.

7. International Association for the Study of Pain (IASP). (2020). Classification of Chronic Pain.

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Published

2025-11-08