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THE CORPUSCULAR ELEMENTS OF BLOOD

Authors

  • Burxonov shohjaxon Abduhakim o’g’li

    Samarqand State Medical University, Samarkand, Uzbekistan
    Author
  • Asatullayev Rustam Bakhtiyorovich

    Scientific supervisor
    Author

Keywords:

corpuscular elements, erythrocytes, leukocytes, thrombocytes (platelets), hematopoiesis, anemia, leukemia, thrombocytopenia, complete blood count (CBC), AI in hematology, gene therapy, liquid biopsy

Abstract

Blood is a specialized connective tissue composed of plasma and corpuscular (cellular) elements. The corpuscular elements include erythrocytes (red blood cells), leukocytes (white blood cells), and thrombocytes (platelets). They constitute approximately 45% of total blood volume and play critical roles in oxygen transport, immune defense, and hemostasis. This scientific review provides an in-depth analysis of the morphology, physiology, hematopoiesis, laboratory diagnostics, clinical significance, and the latest research findings (2025–2026) on blood corpuscular elements, including CRISPR-based gene therapy, artificial intelligence (AI) in blood smear analysis, and novel functions of platelets. The article serves as a comprehensive resource for modern hematology and clinical medicine.

References

1. Frangoul H, et al. Long-term follow-up of exagamglogene autotemcel for sickle cell disease. Blood, 2025.

2. Deltadahl S, et al. Deep generative classification of blood cell morphology (CytoDiffusion). Nature Machine Intelligence, 2025.

3. Murphy L, et al. Platelets as DNA scavengers. Science, 2025.

4. ASH Annual Meeting Abstracts (2025) – Gene Therapies and Classical Hematology.

5. Targeted Oncology. Ropeginterferon alfa-2b in essential thrombocythemia, 2025.

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Published

2026-04-04