MODERN CHALLENGES AND SAFETY PROTOCOLS IN BLOOD TRANSFUSION MEDICINE
Keywords:
Hemotransfusion, Blood Components, Immunological Safety, Erythrocyte Mass, Clinical Protocol, Samarkand, UzbekistanAbstract
Blood transfusion, or hemotransfusion, is a critical therapeutic intervention that saves millions of lives annually. However, it carries inherent risks including immunological reactions and the transmission of infectious diseases. This paper examines the current clinical standards of blood component therapy, focusing on the shift from whole blood to targeted component usage. It analyzes safety protocols such as ABO/Rh compatibility testing and biological screening within the healthcare framework of Uzbekistan. The results emphasize that rigorous adherence to pre-transfusion verification and the promotion of voluntary donation are essential for minimizing adverse outcomes and improving patient survival rates in emergency and surgical settings
References
1. World Health Organization. (2025). Global status report on blood safety and availability.
2. Kumar, V., Abbas, A. K., & Aster, J. C. (2020). Robbins and Cotran Pathologic Basis of Disease (10th ed.). Elsevier.
3. Ministry of Health of the Republic of Uzbekistan. (2024). National standards for blood transfusion and component therapy.
4. Bickley, L. S. (2021). Bates’ Guide to Physical Examination and History Taking (13th ed.). Wolters Kluwer.
5. Regional healthcare assessment data, Samarkand State Medical University (2024–2025).


