1-SIKLOPROPILBUTANDION-1,3 NING FORMILGIDRAZID BILAN HOSIL QILGAN BIRIKMALARINING XOSSALARI
Keywords:
β-diketon, formilgidrazid, pirazol, kondensatsiya reaksiyasi, sikllanish, geterosiklik birikmalar, organik sintez.Abstract
1-siklopropilbutandion-1,3 ning formilgidrazid bilan reaksiyasi natijasida hosil bo‘ladigan geterosiklik birikmalar, ularning sintez mexanizmi, tuzilishi va amaliy ahamiyati yoritilgan. β-diketonlar va gidrazidlarning o‘zaro ta’siri natijasida pirazol hosilalari hosil bo‘lishi organik sintezning muhim yo‘nalishlaridan biri hisoblanadi. Pirazol hosilalari farmatsevtika, biokimyo va qishloq xo‘jaligi sohalarida keng qo‘llaniladi. Tadqiqotlar natijasida ushbu sinf birikmalarining biologik faolligi yuqori ekanligi aniqlangan. Shu sababli 1-siklopropilbutandion-1,3 asosida yangi pirazol hosilalarini olish va ularning xossalarini o‘rganish dolzarb ilmiy masalalardan biri hisoblanadi.
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